Publications

Julia Carrasco-Zanini, Maik Pietzner, Jonathan Davitte, Praveen Surendran, Damien C. Croteau-Chonka, Chloe Robins, Ana Torralbo, Chris Tomlinson, Florian Grünschläger, Natalie Fitzpatrick, Cai Ytsma, Tokuwa Kanno, Stephan Gade, Daniel Freitag, Frederik Ziebell, Simon Haas, Spiros Denaxas, Joanna C. Betts, Nicholas J. Wareham, Harry Hemingway, Robert A. Scott, Claudia Langenberg (2024). Proteomic signatures improve risk prediction for common and rare diseases. Nat Med.

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Ashkan Dashtban, Mehrdad A. Mizani, Laura Pasea, Chris Tomlinson, Yi Mu, Nazrul Islam, Sarah Rafferty, Charlotte Warren-Gash, Spiros Denaxas, Kim Horstmanshof, Evangelos Kontopantelis, Steffen Petersen, Cathie Sudlow, Kamlesh Khunti, Amitava Banerjee, on behalf of the CVD-COVID-UK Consortium (2024). Vaccinations, cardiovascular drugs, hospitalization, and mortality in COVID-19 and Long COVID. IJID.

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Simon Ellershaw, Chris Tomlinson, Oliver E Burton, Thomas Frost, John Gerrard Hanrahan, Danyal Zaman Khan, Hugo Layard Horsfall, Mollie Little, Evaleen Malgapo, Joachim Starup-Hansen, Jack Ross, Martinique Vella-Baldacchino, Kawsar Noor, Anoop D. Shah, Richard Dobson (2024). Automated Generation of Hospital Discharge Summaries Using Clinical Guidelines and Large Language Models. AAAI 2024 SSS on Clinical FMs.

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Marta Pineda-Moncusí, Freya Allery, Antonella Delmestri, Thomas Bolton, John Nolan, Johan Thygesen, Alex Handy, Amitava Banerjee, Spiros Denaxas, Chris Tomlinson, Alastair K Denniston, Cathie Sudlow, Ashley Akbari, Angela Wood, Gary S Collins, Irene Petersen, Kamlesh Khunti, Daniel Prieto-Alhambra, Sara Khalid, on behalf of the CVD-COVID-UK Consortium (2024). Ethnicity data resource in population-wide health records: completeness, coverage and granularity of diversity. Nature Scientific Data.

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Yi Mu, Ashkan Dashtban, Mehrdad A. Mizani, Chris Tomlinson, Mohamed Mohamed, Mark Ashworth, Mamas Mamas, Rouven Priedon, Steffen Petersen, Evan Kontopantelis, Christina Pagel, Mevhibe Hocaoglu, Kamlesh Khunti, Richard Williams, Johan Thygesen, Paula Lorgelly, Manuel Gomes, Melissa Heightman, Amitava Banerjee, on behalf of the CVD-COVID-UK Consortium (2023). Healthcare Utilisation of 282,080 Individuals with Long COVID Over Two Years: A Multiple Matched Control Cohort Analysis. SSRN.

Dataset DOI

Johan Thygesen, Huayu Zhang, Hanane Issa, Jinge Wu, Tuankasfee Hama, Ana Caterina Phiho Gomes, Tudor Groza, Sara Khalid, Tom Lumbers, Mevhibe Hocaoglu, Kamlesh Khunti, Rouven Priedon, Amitava Banerjee, Nikolas Pontikos, Chris Tomlinson, Ana Torralbo, Paul Taylor, Cathie Sudlow, Spiros Denaxas, Harry Hemingway, Honghan Wu, on behalf of the CVD-COVID-UK Consortium (2023). A nationwide study of 331 rare diseases among 58 million individuals: prevalence, demographics, and COVID-19 outcomes. medRxiv.

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Freya Allery, Marta Pineda-Moncusí, Chris Tomlinson, Nikolas Pontikos, Johan Thygesen, Sara Khalid, on behalf of the CVD-COVID-UK Consortium (2023). Towards mitigating health inequity via machine learning: a nationwide cohort study to develop and validate ethnicity-specific models for prediction of cardiovascular disease risk in COVID-19 patients. medRxiv.

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Julia Carrasco-Zanini, Maik Pietzner, Jonathan Davitte, Praveen Surendran, Damien C. Croteau-Chonka, Chloe Robins, Ana Torralbo, Chris Tomlinson, Natalie Fitzpatrick, Cai Ytsma, Tokuwa Kanno, Stephan Gade, Daniel Freitag, Frederik Ziebell, Spiros Denaxas, Joanna C. Betts, Nicholas J. Wareham, Harry Hemingway, Robert A. Scott, Claudia Langenberg (2023). Proteomic prediction of common and rare diseases. medRxiv.

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Harrison Wilde, Chris Tomlinson, Bilal A Mateen, David Selby, Hari Krishnan Kanthimathinathan, Padmanabhan Ramnarayan, Pascale Du Pre, Mae Johnson, Nazima Pathan, Arturo Gonzalez-Izquierdo, Alvina G Lai, Deepti Gurdasani, Christina Pagel, Spiros Denaxas, Sebastian Vollmer, Katherine Brown, on behalf of the CVD-COVID-UK/COVID-IMPACT consortium (2023). Hospital admissions linked to SARS-CoV-2 infection in children and adolescents: cohort study of 3.2 million first ascertained infections in England. BMJ.

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Easan Anand, Saqib Rahman, Chris Tomlinson, Stuart Mercer, Philip Pucher (2023). Comparison of major abdominal emergency surgery outcomes across organisational models of emergency surgical care: analysis of the UK NELA national database. JTACS.

Dataset DOI

Christina Pagel, Harrison Wilde, Chris Tomlinson, Bilal Mateen, Katherine Brown (2023). A Methodological Framework for Assessing the Benefit of SARS-CoV-2 Vaccination following Previous Infection: Case Study of Five- to Eleven-Year-Olds. Vaccines.

DOI

Caroline E Dale, Rohan Takhar, Raymond Carragher, Michalis Katsoulis, Fatemeh Torabi, Stephen Duffield, Seamus Kent, Tanja Mueller, Amanj Kurdi, Stuart McTaggart, Hoda Abbasizanjani, Sam Hollings, Andrew Scourfield, Ronan Lyons, Rowena Griffiths, Jane Lyons, Gareth Davies, Daniel Harris, Alex Handy, Mehrdad Alizadeh Mizani, Chris Tomlinson, Johan Thygesen, Mark Ashworth, Spiros Denaxas, Amitava Banerjee, Jonathan Sterne, Paul Brown, Ian Bullard, Rouven Priedon, Mamas A Mamas, Ann Slee, Paula Lorgelly, Munir Pirmohamed, Kamlesh Khunti, Andrew Morris, Cathie Sudlow, Ashley Akbari, Marion Bennie, Naveed Sattar, Reecha Sofat, CVD-COVID-UK Consortium (2023). The impact of the COVID-19 pandemic on cardiovascular disease prevention and management. Nat Med.

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Mizani, Mehrdad A. and Dashtban, Muhammad and Pasea, Laura and Lai, Alvina and Thygesen, Johan Hilge, Chris Tomlinson, and Handy, Alex and Mamza, Jil Billy and Morris, Tamsin and Khalid, Sara and Zaccardi, Francesco and Macleod, Mary J. and Torabi, Fatemeh and Canoy, Dexter and Akbari, Ashley and Berry, Colin and Bolton, Thomas and Nolan, John and Khunti, Kamlesh and Denaxas, Spiros and Hemingway, Harry and Sudlow, Cathie and Banerjee, Amitava and Consortium, CVD-COVID-UK (2022). Using national electronic health records for pandemic preparedness: validation of a parsimonious model for predicting excess deaths among those with COVID-19–a data-driven retrospective cohort study. JRSM.

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Marta Pineda-Moncusí, Freya Allery, Antonella Delmestri, Thomas Bolton, John Nolan, Johan Thygesen, Alex Handy, Amitava Banerjee, Spiros Denaxas, Chris Tomlinson, Alastair K Denniston, Cathie Sudlow, Ashley Akbari, Angela Wood, Gary S Collins, Irene Petersen, Kamlesh Khunti, Daniel Prieto-Alhambra, Sara Khalid, on behalf of the CVD-COVID-UK Consortium (2022). Digital ethnicity data in population-wide electronic health records in England: a description of completeness, coverage, and granularity of diversity. medRxiv.

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Rochelle Knight, Venexia Walker, Samantha Ip, Jennifer A Cooper, Thomas Bolton, Spencer Keene, Rachel Denholm, Ashley Akbari, Hoda Abbasizanjani, Fatemeh Torabi, Efosa Omigie, Sam Hollings, Teri-Louise North, Renin Toms, Xiyun Jiang, Emanuele Di Angelantonio, Spiros Denaxas, Johan H Thygesen, Chris Tomlinson, Ben Bray, Craig J Smith, Mark Barber, Kamlesh Khunti, George Davey Smith, Nishi Chaturvedi, Cathie Sudlow, William N Whiteley, Angela M Wood, Jonathan A C Sterne, CVD-COVID-UK/COVID-IMPACT consortium, Longitudinal Health and Wellbeing COVID-19 National Core Study (2022). Association of COVID-19 With Major Arterial and Venous Thrombotic Diseases: A Population-Wide Cohort Study of 48 Million Adults in England and Wales. Circulation.

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Chris Tomlinson, Jan Grols, Ramit Debnath, Sarah Johnson, Max Barton, Tianyu Han, Seyedeh Nazanin Khatami, Giacomo Baldo, Aniketh Ramesh, Diego Cammarano, Kashif Rajpoot (2022). Automating perfusion assessment of sublingual microcirculation in critical illness.

DOI

Johan H Thygesen, Chris Tomlinson, Sam Hollings, Mehrdad Mizani, Alex Handy, Ashley Akbari, Amitava Banerjee, Jennifer Cooper, Alvina Lai, Ken Li, Bilal Mateen, Naveed Sattar, Reecha Sofat, Ana Torralbo, Honghan Wu, Angela Wood, Jonathan A C Sterne, Christina Pagel, William Whiteley, Cathie Sudlow, Harry Hemingway, Spiros Denaxas, on behalf of the CVD-COVID-UK Consortium (2022). COVID-19 trajectories among 57 million adults in England: a cohort study using electronic health records. Lancet Digital Health.

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Alex Handy, Amitava Banerjee, Angela Wood, Caroline Dale, Cathie Sudlow, Chris Tomlinson, Daniel Bean, Johan H Thygesen, Mehrdad A Mizani, Michail Katsoulis, Rohan Takhar, Sam Hollings, Spiros Denaxas, Venexia Walker, Richard Dobson, Reecha Sofat & CVD-COVID-UK Consortium (2022). Evaluation of antithrombotic use and COVID-19 outcomes in a nationwide atrial fibrillation cohort. Heart.

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Mizani, Mehrdad A. and Dashtban, Muhammad and Pasea, Laura and Lai, Alvina and Thygesen, Johan Hilge, Chris Tomlinson, and Handy, Alex and Mamza, Jil Billy and Morris, Tamsin and Khalid, Sara and Zaccardi, Francesco and Macleod, Mary J. and Torabi, Fatemeh and Canoy, Dexter and Akbari, Ashley and Berry, Colin and Bolton, Thomas and Nolan, John and Khunti, Kamlesh and Denaxas, Spiros and Hemingway, Harry and Sudlow, Cathie and Banerjee, Amitava and Consortium, CVD-COVID-UK (2022). Using national electronic health records for pandemic preparedness: validation of a parsimonious model for predicting excess deaths among those with COVID-19. SSRN.

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Caroline E Dale, Rohan Takhar, Ray Carragher, Fatemeh Torabi, Michalis Katsoulis, Stephen Duffield, Seamus Kent, Tanja Mueller, Amanj Kurdi, Stuart McTaggart, Hoda Abbasizanjani, Sam Hollings, Andrew Scourfield, Ronan Lyons, Rowena Griffiths, Jane Lyons, Gareth Davies, Dan Harris, Alex Handy, Mehrdad Alizadeh Mizani, Chris Tomlinson, Mark Ashworth, Spiros Denaxas, Jonathan Sterne, Kate Lovibond, Paul Brown, Ian Bullard, Rouven Priedon, Mamas A Mamas, Ann Slee, Paula Lorgelly, Munir Pirmohamed, Kamlesh Khunti, Naveed Sattar, Andrew Morris, Cathie Sudlow, Ashley Akbari, Marion Bennie, Reecha Sofat (2022). The adverse impact of COVID-19 pandemic on cardiovascular disease prevention and management in England, Scotland and Wales: A population-scale descriptive analysis of trends in medication data. medRxiv.

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Alex Handy, Angela Wood, Cathie Sudlow, Chris Tomlinson, Frank Kee, Johan H Thygesen, Mohammad Mamouei, Reecha Sofat, Richard Dobson, Samantha Ip, Spiros Denaxas, on behalf of the CVD-COVID-UK Consortium (2021). A nationwide deep learning pipeline to predict stroke and COVID-19 death in atrial fibrillation. medRxiv.

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Rochelle Knight, Venexia Walker, Samantha Ip, Jennifer A Cooper, Thomas Bolton, Spencer Keene, Rachel Denholm, Ashley Akbari, Hoda Abbasizanjani, Fatemeh Torabi, Efosa Omigie, Sam Hollings, Teri-Louise North, Renin Toms, Emanuele Di Angelantonio, Spiros Denaxas, Johan H Thygesen, Chris Tomlinson, Ben Bray, Craig J Smith, Mark Barber, George Davey Smith, Nishi Chaturvedi, Cathie Sudlow, William N Whiteley, Angela Wood, Jonathan A C Sterne, CVD-COVID-UK/COVID-IMPACT consortium, Longitudinal Health and Wellbeing COVID-19 National Core Study (2021). Association of COVID-19 with arterial and venous vascular diseases: a population-wide cohort study of 48 million adults in England and Wales. medRxiv.

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Johan H Thygesen, Chris Tomlinson, Sam Hollings, Mehrdad Mizani, Alex Handy, Ashley Akbari, Amitava Banerjee, Jennifer Cooper, Alvina Lai, Ken Li, Bilal Mateen, Naveed Sattar, Reecha Sofat, Ana Torralbo, Honghan Wu, Angela Wood, Jonathan A C Sterne, Christina Pagel, William Whiteley, Cathie Sudlow, Harry Hemingway, Spiros Denaxas, on behalf of the CVD-COVID-UK Consortium (2021). Understanding COVID-19 trajectories from a nationwide linked electronic health record cohort of 56 million people: phenotypes, severity, waves & vaccination. medRxiv.

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Gurdasani D, Bhatt S, Costello A, Denaxas S, Flaxman S, Greenhalgh T, Griffin S, Hyde Z, Katzourakis A, McKee M, Michie S, Ratmann O, Reicher S, Scally G, Chris Tomlinson, Yates C, Ziauddeen H & Pagel C (2021). Vaccinating adolescents against SARS-CoV-2 in England: a risk–benefit analysis. JRSM.

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Alex Handy, Amitava Banerjee, Angela Wood, Caroline Dale, Cathie Sudlow, Chris Tomlinson, Daniel Bean, Johan H Thygesen, Mehrdad A Mizani, Michail Katsoulis, Reecha Sofat, Richard Dobson, Rohan Takhar, Sam Hollings, Spiros Denaxas, Venexia Walker & CVD-COVID-UK Consortium (2021). Evaluation of antithrombotic use and COVID-19 outcomes in a nationwide atrial fibrillation cohort. medRxiv.

PDF Code Slides Video DOI

Gurdasani D, Bhatt S, Costello A, Denaxas S, Flaxman S, Greenhalgh T, Griffin S, Hyde Z, Katzourakis A, McKee M, Michie S, Ratmann O, Reicher S, Scally G, Chris Tomlinson, Yates C, Ziauddeen H & Pagel C (2021). Vaccinating adolescents in England: a risk-benefit analysis. OSF Preprints.

Dataset DOI

Angela Wood, Rachel Denholm, Sam Hollings, Jennifer Cooper, Samantha Ip, Venexia Walker, Spiros Denaxas, Ashley Akbari, Amitava Banerjee, William Whiteley, Alvina Lai, Jonathan Sterne, Cathie Sudlow on behalf of the CVD-COVID-UK consortium (2021). Linked electronic health records for research on a nationwide cohort of more than 54 million people in England: data resource. BMJ.

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H. A. Iliff, K. A. Simpson, Chris Tomlinson, C. M. Webb on behalf of Anaesthetists, Intensivists Shielding (2020). ‘Shielded’ anaesthetists and intensivists during the COVID‐19 pandemic. Anaesthesia.

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Chris Tomlinson (2020). Lifelong Learning Platform: untapped analytical potential?. Anaesthesia.

DOI

Chris Tomlinson (2018). The Cauldron: Overcoming Obsolescence (Abstract). JICS.

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